Enlightening the Fully Informed

Enlightening the adrenal gland.

The secretion of glucocorticoid hormones is tightly regulated by the circadian clock and by negative humoral feedback loops, both acting on the hypothalamic-pituitary gland-adrenal axis. However, a new study Ishida et al., 2005 [this issue of Cell Metabolism) shows that light can influence the adrenal's glucocorticoid output by a more direct pathway.

Difficulties in giving fully informed consent.

Enlightening the Postsynaptic Density

1974; Landis et al., 1974; Peters et al., 1991). Related structures are also found at the neuromuscular junction The postsynaptic density (PSD) is a specialization of the (Sanes, 1997). Major morphological variants of type 1 cytoskeleton at the synaptic junction. It lies adjacent to synapses include axodendritic synaptic junctions formed the cytoplasmic face of the postsynaptic membrane, in on ...

Fully informed consent can be needlessly cruel.

levels in the metabolic derangement of diabetes. N Engl J. Med 1984;310: 810-5. 19 Hyer SL, Sharp PS, Brooks RA, Burrin JM, Kohner EM. Serum IGF-1 concentration in diabetic retinopathy. Diabetic Med 1988;5:356-60. 20 Sharp PS, Fallon TJ, Brazier OJ, Sandler L, Joplin GF, Kohner EM. Long term follow up of patients who underwent yttrium-90 pituitary implantation for treatment of proliferative ret...

An Enlightening Reactor

I n recent years, the reaction vessel by which chemists perform organic reactions has undergone major changes. No longer limited to round-bottom flasks, we can perform experiments in microwave ovens, flow reactors, and 96-well plates. Each of these technologies has enabled breakthroughs in organic synthesis not easily achieved using conventional flasks. In the rapid development of photoredox te...